2 (3–12)), Post-treatment Eckardt score was 0.3 (0–1). Complications related to operation included mucosa rupture in 1 (6.3%), mediastinal and subcutaneous emphysema in 4 (25%), asymptomatic pneumothorax in 2 (12.5%), gas under diaphram in 1 (6.3%). All the complications were cured by conservative treatments. ALL patients were follow-up, and no other post operation complications occurred. Conclusion: POEM is an effective, feasible and safe therapy

for achalasia, while the long-term efficacy and managements for complications are still to be elucidated. Key Word(s): 1. POEM; 2. Achalasia; Presenting Author: JINGJING WEI Additional Authors: ZEHAO BGB324 ZHUANG, JIAYUAN ZHUANG, DUPENG TANG, YILIN ZENG, CHENGDANG WANG Corresponding Author: ZEHAO ZHUANG Objective: To investigate the prevalence of gastroesophageal reflux disease (GERD) in the Hakkas and to evaluate the practicability of two questionnaires, including Chinese gastroesophageal reflux disease questionnaire

(CGQ) and gastroesophageal reflux disease questionnaire (GerdQ) in this population. Methods: CGQ and GerdQ were used for GERD symptoms survey in a random sequence in a selected Hakkas community. Results: Paired questionnaires were collected from 203 subjects, including 104 males and 99 females. The positive rates were 12.3% and 4.9% by CGQ and GerdQ, respectively (P < 0.05). A male predominant trendcy was found in GERD symptom positive cases surveyed by GerdQ (P < 0.05), but not in those surveyed

by PD0325901 CGQ (P > 0.05). The incidence of GERD showed an increasing tendency with the aging, through no significant difference was found in age-stratification analysis. The response time was 3.2 ± 0.8 min (CGQ) and 5.4 ± 0.6 min (GerdQ) respectively (P < 0.05). Conclusion: GERD symptoms were quite common in selected Hakkas community, while CGQ surveying showed a higher symptom positive rate than GerdQ surveying in this population. Key Word(s): 1. GERD; 2. GerdQ; 3. Chinese GerdQ; 4. hakka dialect; Presenting Author: LIULIU WEI Additional Authors: HONG CAI Corresponding 上海皓元 Author: LIULIU WEI Affiliations: Ganzhou city people’s hospital; Objective: To investigate the clinical characteristics and risk factors of gastroduodenal damages induced by nonsteroidal anti-inflammatory drugs (NSAIDs). Strengthen to understand the disease. Methods: The sample consisted of 85 patients whose gastroduodenal damages were induced by nonsteroidal anti-inflammatory drugs (NSAIDs) at Ganzhou city people’s hospital from the January 2011 to April 2013. According to the endoscopic diagnosis, the patients were divided into two groups, erosive gastritis group and ulcer group. Record the patients’ age, sex, clinical symptoms, previous ulcer history, H. pylori infection, smoking history and kinds of NSAIDs. Results: ① Of 85 patients of gastroduodenal damages induced by NSAIDs, male 49, female 36, the male and female ratio 1.36 : 1, mean age (61.8 ± 13.