\n\nProspectively collected data were retrospectively analyzed for morbidity, mortality, pre- and postprocedure symptom scores (scale 0-3), body mass index (BMI), and

patient satisfaction (scale 1-10).\n\nSeventy-two patients with 1-4 (median 1) previous antireflux procedures underwent RNY reconstruction, either to gastric pouch (n = 64) or to the esophagus (n = 8). There were 37 laparoscopic, Quisinostat 24 open abdominal, and two combined thoracic-abdominal procedures. Nine additional patients underwent conversion from laparoscopy to open surgery. Mean follow-up of 20.7 months (+/- 12.9 months) was available in 63 (88%) patients. The overall median scores for heartburn, regurgitation, dysphagia, chest pain, and nausea were 0 or 1. There were 72 major and minor complications noted that affected 33 (46%) patients, with no in-hospital or 30-day mortality observed. The most common complications were anastomotic strictures, bowel obstructions, respiratory complications, and dumping. Mean postoperative BMI was 24.6 (+/- 4.4) kg/m(2) compared with preoperative BMI of 31.4 (+/- 6.1) kg/m(2). Mean reported satisfaction score was 8.2 (+/- 2.1), and 89% of the patients would recommend the procedure to a friend. Pre- and postoperative symptoms could be compared in 57 patients, and significant decrease in median symptom scores for heartburn

(2-0, P < 0.05), regurgitation (1-0, P < 0.05), and dysphagia (2-0, P < 0.05) was Akt inhibitor confirmed. There was an increase in reported nausea (0-1, P < 0.05).\n\nShort-limb RNY reconstruction is an effective remedial procedure for a subset of patients with failed antireflux surgery, but morbidity is significant.”
“A simple high-performance liquid chromatography (HPLC) method coupled with principal component analysis (PCA) and hierarchical cluster analysis (HCA) was developed for distinguishing Astragali Radix from its adulterants.

Five species, including A. membranaceus var. mongolicus, A. membranaceus, Quizartinib mouse H. polybotrys, A. chrysopterus and A. ernestii, were analyzed by this method. At the same time, four major bioactive isoflavonoids, namely calycosin-7-O-D-glucopyranoside, ononin, calycosin and formononetin, were simultaneously determined in Astragali Radix. This method was proven to have good precision, repeatability, stability and recovery. It was successfully applied to distinguish Astragali Radix from its adulterants species and can be used for the quality control of Astragali Radix.”
“Decadal to centennial land-cover changes are important drivers of many environmental issues, including biodiversity, biogeochemical cycles and, especially, the global carbon balance. In general, changes are well documented over only a few decades. Studies of land-cover changes and its drivers over centuries are rare.