Conclusions Although studies have yielded contradictory results on the association between stress and breast cancer development, our results confirm that high-intensity stress has a borderline association with the development

of breast cancer. However, relative to the findings in most Lenvatinib clinical trial of studies that stress can increase the risk of breast cancer, whether those women who had the most aggressive form of breast cancer also had the highest stress levels was unclear, and there is no real way to tell how much stress the women were under before their diagnosis of breast cancer. Obviously, based on that it’s not clear what’s driving the association between stress and breast cancer development, future studies are necessary to elucidate this relationship. References 1. Jemal A, Bray F, Center MM, Ferlay J, Ward E, Forman D: Global cancer statistics. CA Cancer J Clin 2011, 61:69–90.PubMedCrossRef 2. Tyrer J, Duffy SW, Cuzick J: A breast cancer prediction model

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