The optimized conditions were then tested in a 7 L bioreactor; a maximum cell weight of 10.2 g L-1 was obtained. CGP comprised 23 g g-1 of cell dry matter (CDM) with molecular weight between 21.5 and 31 kDa and was composed of aspartic acid, arginine and lysine in the ratio of 1.05:1:0.2 (mass basis). Conclusion
The efficient use of renewable selleck screening library biomass for cyanophycin production could achieve competitive price, and in return, promote the use of this platform chemical to produce innovative polymers and materials.(c) 2012 Society of Chemical Industry”
“Cholangiocarcinoma is a rare cancer. Although rare, it remains the second most common hepatobiliary cancer and its incidence is increasing worldwide. Extrahepatic cholangiocarcinoma can occur anywhere along the biliary tree and prognosis varies according to the location of disease.”
“We
GSK1838705A inhibitor evaluated the reliability and validity of the Pediatric Functional Assessment of Cancer Therapy-Childhood Brain Tumor Survivor version 2.0 (pedsFACT-BrS; patient version for grade school children aged 7-12 years).
After translating and cross-culturally adapting it into Korean, the psychometric properties of the pedsFACT-BrS were evaluated in 148 childhood brain tumor survivors (mean age, 9.67 years). Pre-testing was performed in 25 patients.
The pedsFACT-BrS showed good symptom coverage and overall user comprehension. Internal consistency was acceptable, with Cronbach’s
alpha coefficients ranging from 0.70 to 0.92. The pedsFACT-BrS also demonstrated good convergent and divergent validities when correlated with the Revised Children’s Manifest Anxiety Scale and Kovacs’ Children’s Depression Scale. The pedsFACT-BrS showed good known-group validity and effectively differentiated between clinically distinct patient groups (patient vs. control groups, and among patients having different Karnofsky scores), but offered only partial discrimination of physical well-being (PWB) scores when patients were grouped by treatment type.
Our results indicate Combretastatin A4 Cytoskeletal Signaling inhibitor that this instrument is reliable and valid and can be used to evaluate the quality of life of Korean childhood brain tumor survivors.”
“Background Functionalization of aliphatic biopolymers such as bacterial polyhydroxyalkanoates (PHA) using biologically active hydrophilic moieties like sugars helps to improve the hydrophilicity and biodegradability of the biomaterial. Results The effects of reaction variables reaction time, temperature, enzyme concentration and substrate ratio on reaction rate and yield in the synthesis of poly(1′-O-3-hydroxyacyl-sucrose) using Candida antarctica lipase B (EC 3.1.1.3) were studied. Using H2O2 as micro-initiator, enzyme-mediated synthesis yielded reaction rate, vapp of 0.076 x 10-5 mol L-1 s-1. The biodegradability of the functionalized polymer was observed to increase by 1.