Using region of interest (ROI)-based analysis, we compared CC volumes from 58 children and adults affected by 22q11DS with 64 healthy age- and gender-matched controls. After covarying for total cranium grey matter and age, a bilateral reduced CC grey matter volume, driven by a decrease in anterior CC cortex, was observed among 22q11DS click here patients. Further post hoc analyses Suggest correlations between right CC cortical reductions, low-executive functioning and the Occurrence of psychotic symptoms. The CC structural abnormalities observed in 22q11DS are consistent with previous

reports in schizophrenic patients and are associated with pre-morbid cognitive impairments. The mechanisms by which these changes may modulate executive functioning and the expression of psychosis are discussed. (C) 2008 Elsevier Ltd. All rights reserved.”
“Objectives. Numerous studies have documented disparities in health care utilization between 5-Fluoracil non-Hispanic White and minority elders. We investigated differences in anti-dementia medication use between non-Hispanic White and minority community-dwelling Medicare beneficiaries with dementia.

Methods. Using multivariate analysis with generalized estimating equations, we estimated prevalence ratios (PRs) for anti-dementia medication use by race/ethnicity for 1,120 beneficiaries with dementia from

years 2001 through 2003 of the Medicare Current Beneficiary Survey.

Results. After adjusting for demographics, socioeconomics, health care access and utilization, comorbidities, and service year, we found that anti-dementia medication use was approximately 30% higher among non-Hispanic Whites compared to other racial/ethnic groups (PR = 0.73, 95% confidence interval selleck compound [CI] = 0.59, 0.91). As for individual racial/ethnic groups, prevalence

disparities remained significant for non-Hispanic Blacks (PR = 0.75, 95% CI = 0.57, 0.99) and non-Hispanic others (PR = 0.50, 95% CI = 0.26,. 0.96) but were attenuated tor Hispanics (PR = 0.84, 95% CI = 0.59, 1.20).

Discussion. Results provide evidence that racial/ethnic disparities in utilization of drugs used to treat dementia exist and are not accounted for by differences in demographic, economic, health Status, or health utilization factors. Findings provide a foundation for further research that should use larger numbers of minority patients and consider dementia type and severity. access to specialty dementia care, and cultural factors.”
“Autobiographical memory relies on complex interactions between episodic memory contents, associated emotions and a sense of self-continuity over the course of one’s life. This paper reports a study based upon the case of the patient NN who Suffered from a complete loss of autobiographical memory and awareness of identity subsequent to a dissociative fugue.