We previously reported that an increased visceral fat area (VFA) determined using computed tomography scans was associated with atherosclerosis in hemodialysis patients. However, whether a high VFA is associated with increased cardiovascular mortality in hemodialysis patients remains unknown. Therefore, we investigated the relationship between VFA and prognosis in hemodialysis patients. Methods: VFA

check details was estimated in 126 patients on maintenance hemodialysis using computed tomography scans. These patients were followed for 60 months. Results: Kaplan-Meier analysis revealed that the cardiovascular survival rate was significantly lower in the high VFA group, with a VFA of 71.5 cm2 or greater, than in the low VFA group, with a VFA of less than 71.5 cm2. Hazards ratio of clinical characteristics of subjects for cardiovascular deaths were see more calculated in the univariate cox analyses. A high VFA, but not high BMI or WC was an independent predictor of cardiovascular deaths. In the multivariable analyses, we adjusted for significant factors such as age, LDL, CTR and High

VFA in univariate analyses. High VFA was an independent predictor of cardiovascular deaths. Conclusion: These results suggest that an increased VFA is a stronger risk factor than body mass index or waist circumference for cardiovascular deaths in hemodialysis patients. Measuring VFA may be recommended for predicting the risk of cardiovascular diseases in hemodialysis patients. In addition, interventions to reduce an increased VFA may be effective in preventing cardiovascular deaths in these patients. PEI-LIN CHUNG1, TSAI JEN-PI2, CHANG CHIEN-HWA3 1Department of Nursing, Buddhist Dalin Tzu Chi General Hospital; 2Department

of Nephrology, Buddhist Dalin Tzu Chi General Hospital; 3Department of Cardiac Surgery, Buddhist Dalin Tzu Chi General Hospital Introduction: Arteriovenous shunt infection is a major morbidity of chronic maintenance hemodialysis (HD) patients. This study was conducted RVX-208 to determine the risk factors at the development of shunt infection. Methods: From 2007 April to 2013 August, there were 1048 patients received shunt creation, which included arteriovenous fistula (AVF), arteriovenous graft (AVG) and arteriovenous fistula transposition (AVFT), and had regular follow up at our hospital. Shunt infection was defined by clinical impressions and wound/blood culture reports. Results: During this period, 54 HD patients (5.13%) were diagnosed to have shunt infection (2 AVF, 49 AVG, 3 AVFT). The pathogens were gram positive 68% (39/57), gram negative 12.3% (7/57), no growth 14% (8/57) and not known 5.3% (3/57). Patients who had shunt infection were older (69.21 ± 10.5 vs. 65.47 ± 12.98, p = 0.015) and used more AVG (90.