“
“Monoamine oxidase (MAO) inhibitors were the first antidepressant drugs to be prescribed and are still used today with great success, especially in patients resistant to other antidepressants. In this study, we evaluated the MAO inhibitory properties and the potential

antidepressant action of 2-(3,4-dimethoxy-phenyl)-4,5-dihydro-1H-imidazole (2-DMPI) in mice. We found that 2-DMPI inhibited both MAO isoforms (K-i values were 1.53 (1.3-1.8) mu M and 46.67 (31.8-68.4) mu M for MAO-A and MAO-B, respectively) with 30-fold higher selectivity toward MAO-A. In relation to the nature of MAO-A inhibition, 2-DMPI showed NU7026 ic50 to be a mixed and reversible inhibitor. The treatment with 2-DMPI (100-1000 mu mol/kg, s.c.) caused a significant decrease in immobility

time in the tail suspension test (TST) without affecting locomotor activity, motor coordination or anxiety-related activities. Conversely, moclobemide (1000 mu mol/kg, s.c.) caused a significant increase in immobility time in the TST, which appeared to be mediated by a nonspecific effect on motor coordination function. 2-DMPI (300 mu mol/kg, s.c.) decreased serotonin turnover in the cerebral cortex, hippocampus and striatum, whereas Compound C PI3K/Akt/mTOR inhibitor dopamine turnover was diminished only in the striatum, and norepinephrine turnover was not changed. The antidepressant-like effect of 2-DMPI was inhibited by the pretreatment of mice with methysergide (2 mg/kg, s.c., a non-selective serotonin 4 receptor antagonist), WAY100635 (0.1 mg/kg, s.c., a selective 5-HT1A receptor antagonist) or haloperidol (0.05 mg/kg, i.p., a non-selective dopamine receptor antagonist). These results suggest that 2-DMPI is a prototype reversible and preferential MAO-A inhibitor with potential antidepressant activity, due to its modulatory effect on serotonergic and dopaminergic systems. (c) 2012 Elsevier Inc. All rights reserved.”
“The operational and analytical performance of two automated triplex Selleckchem LY2157299 hepatitis

B virus (HBV), hepatitis C virus (HCV), and human immunodeficiency virus (HIV) nucleic acid test (NAT) systems were compared in four screening laboratories of the French Blood Service.\n\nTwo laboratories evaluated the Procleix Tigris system (Chiron/Gen-Probe) in individual donation (ID) format and two sites used the cobas s 201 system (Roche Molecular Systems) on minipools (MPs) of six donations. The analytical sensitivity, the specificity, and operational performance were compared.\n\nThe ID to MP-NAT relative sensitivity factors in standard dilution panels of different genotypes varied between 8.7 and 21.9 for HCV RNA, 6.7 and 14.8 for HIV RNA, and 0.71 and 11.6 for HBV DNA. Tigris was 800-fold more sensitive than cobas s 201 (1:6) for a HIV group O sample, but did not detect the HIV-2 sample picked up by cobas s 201 with equal sensitivity as the HIV-1 group M samples. The specificity of both NAT systems after initial screening of 10,520 donations with Tigris and 1444 test pools on s 201 was 99.

For the polyelectrolyte PSS, higher iontophoretic flux was observed in cathodal selleck chemicals iontophoresis compared to anodal iontophoresis. Both electroosmosis and electrophoresis affected iontophoretic fluxes of the macromolecules; the relative contributions of electroosmosis and electrophoresis were a function of molecular size and charge of the macromolecules. (C) 2009 Elsevier B.V. All rights reserved.”
“For self-assembly of the bacterial flagellum, most of the flagellar component proteins

synthesized in the cytoplasm are exported by the flagellar type III export apparatus to the growing, distal end. Flagellar protein export is highly organized and well controlled in every step of the flagellar assembly process. Flagellar-specific chaperones not only facilitate the export of their cognate proteins, as well as prevent their premature aggregation LB-100 in the cytoplasm, but also play a role in fine-tuning flagellar gene expression to be coupled with the flagellar assembly process. FliT is a flagellar-specific chaperone responsible for the export of the. lament-capping protein FliD and for negative control of flagellar gene expression by binding to the FlhDC complex. Here we report the crystal structure of Salmonella FliT at 3.2-angstrom

resolution. The structural and biochemical analyses clearly reveal that the C-terminal segment of FliT regulates its interactions with the FlhDC complex, FliI ATPase, and FliJ (subunits of the export apparatus), and that its conformational change is responsible for the switch in its binding partners during flagellar protein export.”
“Background: The debate over nipple-sparing mastectomy continues to evolve. Over the past several years, it has become more widely accepted, especially in the setting of prophylactic mastectomy, but its role in the treatment of

breast cancer has only recently been reexamined.\n\nMethods: Two indications for the procedure are discussed: prophylactic, for the high-risk patient; and the more controversial topic, therapeutic nipple-sparing mastectomy, for the patient with breast cancer. A review of the literature suggests that certain breast cancers may be amenable to retaining the nipple if they meet specific oncologic criteria: tumor Tozasertib clinical trial size 3 cm or less, at least 2 cm from the nipple, not multicentric, and with clinically negative nodes. Moreover, newer technologies such as magnetic resonance imaging and preoperative mammotome biopsy may make the procedure even safer in this setting. Practical and technical aspects of the procedure are discussed, including patient selection.\n\nResults: The accumulating data from multiple series of nipple-sparing mastectomy show that properly screened patients have a low risk of local cancer recurrence, that recurrences occur rarely in the nipple, and that recurrences in the nipple can be managed by removing the nipple.

“
“BACKGROUND. in men with prostate cancer, pretreatment prostate-specific antigen (PSA) velocity (PSAV) has been demonstrated as a predictor of biochemical and survival

outcomes in patients undergoing radical prostatectomy (RP). The utility of pretreatment PSAV in predicting outcomes after radiotherapy (RT), with or without androgen-deprivation therapy (ADT), is less certain. This study was undertaken to determine whether pretreatment PSAV is associated with biochemical disease-free survival, patterns of selleck recurrence, and survival outcomes in men treated with radiation therapy and ADT.\n\nMETHODS. Two hundred seventy-seven patients with intermediate- and high-risk prostate cancer treated with RT and ADT formed the study cohort. Kaplan-Meier survival estimates and Cox regression analyses were used to evaluate whether PSAV was associated with disease outcomes.\n\nRESULTS. The median age of diagnosis was 70 years, and the median follow-up was 6.8 years. Men with a

PSAV in the highest quartile tended to have higher risk disease at presentation (P =.028). After adjustment for known prognostic factors and 432 duration of ADT, https://www.selleckchem.com/products/rocilinostat-acy-1215.html men who had a PSAV in the highest quartile had an increased risk of distant metastasis (hazard ratio [HR], 4.0; 95% confidence interval [95% CI], 1.61-9.9 [P =.003]) and prostate cancer-specific mortality (HR, 2.75; 95% CI, 1.27-5.95 [P =.01]) compared with men who had a lower PSAV, but had no increase in the risk of local recurrence (P =.76).\n\nCONCLUSIONS. A high pretreatment PSAV was associated

with distant metastasis and prostate cancer-specific mortality but not with local recurrence. A high pretreatment PSAV may signify the presence of occult metastatic disease. Randomized trials are needed to determine whether more aggressive AG-120 Metabolism inhibitor intervention is required in men who present with high pretreatment PSAV.”
“Purpose A high rate of sustained viral response (SVR) in Koreans with chronic hepatitis C (CHC) is related to a favorable IL28B genotype. We compared two dosing strategies for peginterferon alfa-2a in Koreans with CHC and defined the combined effect of polymorphisms and dosing on the virological response.\n\nMethods A total of 178 treatment-na < ve patients with CHC genotype 1 were prospectively enrolled. All patients were randomly assigned to treatment with one of two peginterferon alfa-2a regimens: 180 mu g per week for 48 weeks (full-dose group) or 180 mu g per week during the first 12 weeks followed by 135 mu g per week for the next 36 weeks (dose-reduction group). Polymorphisms related to IL28B, ITPA, C20orf194 and SLC29A1 were studied.\n\nResults SVR rates did not differ between the full-dose and dose-reduction groups (56.5 and 51.2 %, respectively, p = 0.474).

Times to occlusion on a collagen matrix in our model were within the range of occlusion times observed in murine thrombosis models. Prolongation of time to occlusion in the presence of platelet alpha(IIb)beta(3) antagonists or inhibitors to thrombin or activated factor X is in agreement with established mechanisms of thrombus formation. The use of this model may be expanded to characterize the mechanisms of thrombosis and to determine the efficacy of pharmacological agents designed to prevent occlusive thrombus formation.”
“In the original time-domain Bell’s inequalities (Leggett-Garg-type inequalities), the

physical objective is measured at three time points. When more time points are chosen, several methods can be P5091 purchase used to extend these inequalities. We experimentally demonstrate the violation of these extended inequalities using single photons from a self-assembled quantum dot. In general, for each extension, the quantity by which the quantum-mechanics value exceeds the classical limit becomes larger as the number of measurement time points increases. This quantity has a maximum value for the

extensions learn more that have the same number of measurement time points. Furthermore, we evaluate the noise tolerance for these extensions with a quantity that is related to the number of standard deviations by which the experimental result surpasses the classical limit.”
“Aim To describe the successful non-surgical endodontic management of a permanent maxillary lateral incisor tooth with four root canals. Summary Aberrant morphology of root canals can occur in any tooth, including maxillary lateral incisors. In the presented case, clinical examination and radiographs clearly depicted the presence of four

root canals in a right maxillary lateral incisor. The differential GSK1904529A cost diagnosis included fusion, gemination, dens invaginatus or a combination of these. The report emphasises the need for attention during root canal treatment of maxillary lateral incisors. Key learning points Clinicians should be aware of the variable root canal anatomy in maxillary lateral incisor teeth. Careful examination of radiographs and the internal anatomy of teeth are essential prerequisites for successful root canal treatment. Four root canals in maxillary lateral incisors is a possibility.”
“This study examines the area-based variations in obesity from a community-based epidemiologic survey of Boston, MA, USA, using a geographic information system and multilevel modeling techniques. A combination of quantitative and qualitative methods was used to assess whether a function of the food and the physical activity (PA) environment can explain the body weight of residents. First, a series of multilevel analyses was conducted after accounting for the well-established individual determinants and capturing a wide range of environmental attributes to represent a more realistic portrayal of urban typology.

Compared

with a Poly-L-lysine-coated suture technique, the modified suture technique produced a lower rCBF, larger infarct size, smaller variance of infarct size, and greater neurological deficit. In addition, isoflurane significantly reduced infarct size. We conclude that the use of this modified suture technique with ketamine/xylazine anesthesia and mechanical ventilation produces a more consistent change in cerebral ischemic damage following MCAO in rats. (C) 2008 Elsevier B.V. All rights reserved.”
“Polyunsaturated fatty acids (PUFAs) undergo autoxidation and generate reactive carbonyl compounds that are toxic to cells and associated with apoptotic cell death, age-related neurodegenerative diseases, and atherosclerosis. PUFA autoxidation is initiated by the abstraction of bis-allylic hydrogen atoms. Replacement of the bis-allylic hydrogen atoms with deuterium atoms (termed site-specific QNZ isotope-reinforcement) arrests PUFA autoxidation due to the isotope effect. Kinetic competition experiments show that the kinetic isotope effect for the propagation

rate constant of Lin autoxidation compared to that of 11,11-D-2-Lin is selleck chemicals 12.8 +/- 0.6. We investigate the effects of different isotope-reinforced PUFAs and natural PUFAs on the viability of coenzyme Q-deficient Saccharomyces cerevisiae coq mutants and wildtype yeast subjected to copper stress. Cells treated with a C11-BODIPY fluorescent probe to monitor lipid oxidation products show that lipid peroxidation precedes the loss of viability due to H-PUFA toxicity. We show that replacement of just one bis-allylic hydrogen atom with deuterium is sufficient to arrest lipid autoxidation. In contrast, PUFAs reinforced with two deuterium atoms at

mono-allylic sites remain susceptible to autoxidation. Surprisingly, yeast treated with a mixture of approximately learn more 20%:80% isotope-reinforced D-PUFA:natural H-PUFA are protected from lipid autoxidation-mediated cell killing. The findings reported here show that inclusion of only a small fraction of PUFAs deuterated at the bis-allylic sites is sufficient to profoundly inhibit the chain reaction of nondeuterated PUFAs in yeast. (C) 2012 Elsevier Inc. All rights reserved.”
“It is being increasingly recognized that many important phenotypic traits, including various diseases, are governed by a combination of weak genetic effects and their interactions. While the detection of epistatic interactions that involve a non-additive effect of two loci on a quantitative trait is particularly challenging, this interaction type is fundamental for the understanding of genome organization and gene regulation. However, current methods that detect epistatic interactions typically rely on the existence of a strong primary effect, considerably limiting the sensitivity of the search. To fill this gap, we developed a new method, SEE (Symmetric Epistasis Estimation), allowing the genome-wide detection of epistatic interactions without the need for a strong primary effect.

Conclusion: The ASFS-based clinical model was demonstrated to be a reliable and proven methodology to assess the effectiveness of widely used anti-dandruff treatments. The results are consistent with patient self-assessments, establishing this methodology as relevant to patient

perception of product benefits.”
“This C188-9 manufacturer paper analyses the effect of early caponisation, at 18 days, on the production performance, lipid metabolism and fatty acid profile of fattening broilers fed an increased amount of fat. Early castration did not influence growth performance and feed intake in the experimental birds. Feed conversion was significantly improved in castrated birds (P<0.05). Triglyceride and total cholesterol values were not significantly influenced (P>0.05) by early castration. Glucose values were significantly higher on the 25th (P<0.05) and 40th (P<0.01) day in sham operated birds in comparison to castrated. Fatty acid composition of the thigh muscle was significantly influenced by castration. The most noticeable difference was in the increased percentage of saturated fatty acids (P<0.05) in castrated birds in comparison to uncastrated. Moreover, the saturation index and the thrombogenic index were higher (P<0.05) in castrated birds and unsaturated/saturated fatty Raf targets acid ratio was higher

(P<0.05) in uncastrated birds.”
“The proteocephalidean tapeworm Monticellia santafesina n. sp. is described from the siluriform catfish Megalonema platanum (Gunther) (Siluriformes: Pimelodidae) in the Parana River basin, Argentina. The new species is allocated to Monticellia La Rue, 1911 (Proteocephalidae: Monticelliinae) because of the cortical position of the testes, ovary, vitelline follicles and uterus, a globular scolex without a metascolex and uniloculate suckers. The new species differs from all other species of Monticellia (except for M. lenha Woodland, 1933) in possessing a vaginal canal opening anterior or posterior to the cirrus-sac. M. santafesina can be distinguished from M.

lenha by the following characteristics: a larger Geneticin datasheet body size; a weakly developed internal longitudinal musculature arranged in 15-35 slim bundles of muscle fibres; vitelline follicles not interrupted at the level of the cirrus-sac and vaginal canal, and with a few paramuscular and/or medullary follicles; the absence of large spinitriches on the anterior margin of the suckers; and the utilisation of Megalonema platanum (in the Parana River basin) as its host, rather than Sorubimichthys planiceps (Spix & Agassiz) (in the River Amazon). Monticellia santafesina exhibits low values of prevalence (9%) and intensity of infection (1). Megalonema platanum was parasitised by two proteocephalidean cestodes, Rudolphiella cf. lobosa (Riggenbach, 1895) and the new species described in this paper.

Conclusion: The present study found peer relationship quality to be an important antecedent factor of identity formation in adolescents with CHD. Future research should investigate how changes in peer relationships and identity relate to well-being in these patients.”
“The processing of plastics, particularly reinforced composites, necessitates the use of corrosion- and wear-resistant

materials for tools that come into contact with the polymer. For such applications, plastic mold steels were developed that offer not only a good wear resistance due to the presence of carbides Vadimezan in a martensitic matrix, but also good corrosion resistance provided primarily by a sufficient amount of dissolved chromium. The common processing route for these high-alloyed materials is the hot isostatic pressing (HIP) of gas-atomized powders (PM-HIP). In this context, sintering plays an insignificant role, except for the processing of metal-matrix composites (MMCs). The development of novel wear- and corrosion-resistant MMCs based on plastic mold steels requires knowledge of the sintering behavior of prealloyed powders of such tool steels. It is well known that alloyed powders can be processed SB203580 by supersolidus liquid-phase sintering (SLPS),

a method leading to almost full densification and to microstructures without significant coarsening effects. In this work, two Cell Cycle inhibitor different gas-atomized powders of plastic mold steels were investigated by computational thermodynamics, thermal analysis, sintering experiments, and microstructural characterization. The results show that both powders can be sintered to almost full density (1 to 3 pct porosity) by SLPS in a vacuum or a nitrogen atmosphere. Experimental findings on the densification behavior, nitrogen uptake, and carbide volume fractions are in good agreement with calculations performed by computational

thermodynamics.”
“OBJECTIVE: To evaluate the feasibility of reaching the interpeduncular cistern (IC) through an endoscopic endonasal approach that leaves the pituitary gland in place. METHODS: In a series of 10 injected cadaver heads, the transtuberculum (“above”) and transclival (“below”) approaches were combined, without pituitary transposition. Using 0-degree, 30-degree, and 45-degree endoscopes, the extent of overlap and if a blind spot occurred were determined. Also, the visualization of the IC was compared with the transposition of the pituitary gland approach. Nonparametric statistics were used to evaluate the results. The approach was implemented in 2 patients. RESULTS: For both the “above” and “below” views, there was a statistically significant increase in field of view when comparing the 0-degree endoscope with either the 30-degree endoscope (P smaller than 0.05) or the 45-degree endoscope (P smaller than 0.05).

The shorter left main coronary artery that the BAV patients possess may contribute to the progressive course of aortic dilation that these patients experience. Statin therapy did not affect the aortic annulus in either group, but did decrease the dimensions of the

aortic root, Dorsomorphin cell line sinotubular junction and ascending aorta. In general, statin therapy had a better effect on the aortas of the TAV patients than it did on those of the BAV patients.”
“Two functionally related genes, FOXP2 and CNTNAP2, influence language abilities in families with rare syndromic and common nonsyndromic forms of impaired language, respectively. We investigated whether these genes are associated with component phenotypes of dyslexia and measures selleck compound of sequential motor ability. Quantitative transmission disequilibrium testing (QTDT) and linear association modeling were used to evaluate associations with measures of phonological memory (nonword repetition, NWR), expressive language (sentence repetition), reading (real word reading efficiency, RWRE; word attack, WATT), and timed sequential motor activities (rapid alternating place of articulation, RAPA; finger succession in the dominant hand, FS-D) in 188 family trios with a child with dyslexia. Consistent with a prior study of language impairment, QTDT in dyslexia showed evidence of CNTNAP2

single nucleotide polymorphism (SNP) association selleckchem with NWR. For FOXP2, we provide the first evidence for SNP association with component phenotypes of dyslexia, specifically NWR and RWRE but not WATT. In addition, FOXP2 SNP associations with both RAPA and FS-D were observed. Our results confirm the role of CNTNAP2 in NWR in a dyslexia sample and motivate new questions about the effects of FOXP2 in neurodevelopmental disorders.”
“The flower extracts of Teucrium stocksianum were screened

for antioxidant and phytochemical constituents by using nine different solvents such as acetone, butanol, chloroform, ethyl acetate, ethanol, methanol, n-hexane, petroleum ether and water. By using these extracts, 10 phytoconstituents were screened. Saponins detected by all solvents, followed by tannin, reducing sugar (each 7), flavonoids (6), terpenoid (5), alkaloids, anthraquinone (4 each), whereas, steroids detected by 3 and phlobatannin as well as glycoside isolated by 2 solvents. Three solvents viz., chloroform, ethyl acetate and water extracted highest weight of raw material (150 g), followed by petroleum ether (130 g), n-hexane, acetone (120 g each), methanol (118 g). N-hexane yielded highest extract weight (26 g), followed by butanol (20 g), methanol (19.3 g), water (17 g), acetone (14.5 g), chloroform (13.5 g), petroleum (12.3 g) and ethanol (11.4 g).

Based on patients who completed 6 months of treatment, success (more than 90%

reduction in wet nights per month) was achieved in 76.8% and 61.8% of children in the desmopressin and enuretic alarm groups, respectively. At 12 months 77.8% of those receiving desmopressin and 75% of those treated with enuretic alarm had success. However, CA4P long-term success rate was significantly higher with desmopressin (68.8% vs 46.2%) if intention to treat population was considered. Multivariate analysis revealed treatment group, severity of enuresis and monthly income as independent predictors of cure at 6 months. Conclusions: In compliant patients desmopressin lyophilisate and enuretic alarm provided equivalent success at the end of treatment and after extended followup. Alarm therapy had a high rate of early withdrawal from therapy

and consequently lower rates of success on intention to treat analyses. Severe enuresis (more than 5 wet nights weekly) is an important predictive factor for cure after first-line treatment.”
“C-type natriuretic peptide (CNP) is an abundant neuropeptide in the human brain and the cerebrospinal fluid. CNP is involved in anxiogenesis and exerts its effects through the natriuretic peptide receptor B (NPR-B), which is expressed in the hippocampus. Hippocampal network oscillations of distinct frequency bands like gamma (gamma)-oscillations and sharp wave-ripple AZD6738 cell line complexes (SPW-Rs) are likely involved in various cognitive functions such as the storage of information and memory consolidation in vivo. Here, we tested the effects of CNP on distinct network oscillations in horizontal slices of rat hippocampus. We found that CNP decreased the power of stimulus- and ACh/physostigmine-induced gamma-oscillations. In contrast to stimulus-induced gamma-oscillations, CNP increased the frequency of ACh-induced, persistent network oscillations. Moreover, the peptide hormone reduced the incidence of LTP-associated SPW-Rs in selleckchem area CA3 and CA1. Immunohistochemistry indicates that the peptide binds to receptors expressed

on a subset of GAD 65-67-immunopositive cells in addition to binding to principal and other presumably non-neuronal cells. CNP caused a hyperpolarization of CA3 neurons increased their input resistance and decreased inhibitory conductance. Together, our data suggest that the effects of CNP on synchronized hippocampal network oscillations might involve effects on hippocampal interneurons. (C) 2009 IBRO. Published by Elsevier Ltd. All rights reserved.”
“A 29-year-old man was referred to our hospital with fulminant hepatic failure (FHF) and stage III hepatic coma (somnolence and confusion). Living donor liver transplantation (LDLT) was planned for 2 days after admission to our hospital. However, on the day after admission, he lapsed into stage IV hepatic coma: no right reflexes and no response to pain stimuli.

Whole cell patch-clamp recording yielded robust peak I-Na and large late I-Na (1.1% of peak I-Na vs 0.1-0.2% in healthy controls). A large window current was observed as well. Ranolazine (10 M) shifted steady-state V-0.5 of inactivation by -8 mV, reduced late I-Na by 82%, and significantly diminished the window current.\n\nConclusionOur results indicate the presence of cells Blebbistatin cost with M-cell characteristics in the septum of the human heart, as has previously been described in the canine heart. They also point to an ameliorative effect of ranolazine to reduce augmented late I-Na and thus to reduce the prolonged APD

in the setting of HCM. These results suggest a potential therapeutic role for ranolazine in HCM.”
“Objectives:\n\nThis exploratory study compared the screening ability of a newly introduced radiation detection portal with a traditional Geiger counter for detection of radiation contamination in the setting of a mass casualty training exercise.\n\nMethods:\n\nFollowing a pretrial evaluation of interobserver reliability for Geiger counter use, 30 volunteers were randomly assigned to don gowns containing three disks, each of which was either a sham resembling the radioactive samples or an actual cesium-137 sample; each subject participated a minimum of four times with different gowns each time. Each subject underwent standard radioactivity

screening with the Geiger counter and the portal.\n\nResults:\n\nInterobserver reliability was excellent between the two Geiger counter screeners in the pretrial exercise, correctly identifying 101 of Salubrinal 102 sham and radioactive samples (kappa = 0.98; 95% confidence interval [CI] = 0.94 to 1.00). For radioactively labeled subjects across all bodily locations, the portal (43/61, or 70.5%; 95% CI = 58.1% to 80.5%) was less sensitive than the Geiger counter screening (61/61, or 100%; 95% CI = 92.9% to 100%), which

resulted in a portal false-negative rate of 29.5%. For radiation detection in the posterior thorax, the portal radiation screening (4/19, or 21.1%; 95% CI = 8% to 43.9%) was less accurate than the Geiger check details counter (19/19, or 100%; 95% CI 80.2% to 100%). In contrast, there were no major differences between the portal and the Geiger counter for radiation detection at the left shoulder, right shoulder, or sham (nonradiation) detection. There were no false-positive detections of the sham-labeled subjects for either device, yielding a specificity of 100% for both screening modalities.\n\nConclusions:\n\nGeiger counter screening was more sensitive than, and equally specific to, radiation detection portal screening in detecting radioactively labeled subjects during a radiation mass casualty drill.\n\nACADEMIC EMERGENCY MEDICINE 2010; 17:1020-1023 (C) 2010 by the Society for Academic Emergency Medicine.